(1) In a total of 100 patients with
traumatic coma who were admitted to the intensive care unit of our Department
of Neurosurgery we examined the effect of pyritinol
after intravenous
administration.
(2) Compared to patients with the same clinico-neurological
conditions who were, however, not treated with pyritinol, the cases treated
by the preparation did not show any significant clinical improvement.
Moreover, in the pyritinol group mortality rate in patients with an
unfavourable prognosis sank to 35.3% (mortality rate in the comparative group:
54.2%).
(3) Untoward effects on the clinico-neurological condition, cortical
electrogenesis, vegetative functions and body fluid parameters were not
observed after administration of the preparation
